Comparing Kamagra 100 to Sildenafil citrate is the active pharmacological ingredient in Viagra, a well-known drug used to treat erectile dysfunction (ED). Cyclic guanosine monophosphate (cGMP) is the target of sildenafil citrate, a strong selective inhibitor of phosphodiesterase type 5 (PDE5) that efficiently promotes the hemodynamic changes linked to penile erection. It functions by blocking PDE5, which relaxes smooth muscle, raises blood flow to the penis during sexual stimulation, and increases the amount of cGMP in the corpus cavernosum.